Publications

Purification and characterization of recombinant neuraminidase as a potentially broadly protective influenza virus vaccine candidate

Vaccine. 2025 Aug 30;62:127471. doi: 10.1016/j.vaccine.2025.127471. Epub 2025 Jul 11.

PMID: 

40651308

Fernando De Mathia, Tobias Kargl, Matthias Müller, Irfan Erdem, Brooks Hayes, Eduard Puente-Massaguer, Florian Krammer, Nico Lingg

Immunogenicity and protective efficacy of an intranasal neuraminidase-based influenza vaccine with bacterial cell membrane-derived adjuvants

NPJ Vaccines. 2025 Jul 10;10(1):149. doi: 10.1038/s41541-025-01209-7.

PMID: 

40640198

Kirill Vasilev, Irene Hoxie, Eduard Puente-Massaguer, Joshua Yueh, Disha Bhavsar, Maya Singh, Corey P Mallett, Joseph Zimmermann, Florian Krammer

Induction of hemagglutinin stalk reactive antibodies by the administration of a live-attenuated influenza virus vaccine in children

iScience. 2025 Jun 13;28(7):112893. doi: 10.1016/j.isci.2025.112893. eCollection 2025 Jul 18.

PMID: 

40620902

Juan Manuel Carreño, Philip Meade, Na Fatimata Sogodogo, Kaori Sano, Johnstone Tcheou, Ariel Raskin, Gagandeep Singh, Miriam Fried, Madhumathi Loganathan, Benjamin Francis, Dominika Bielak, Ya Jankey Jagne, Hadijatou J Salah, Florian Krammer, Thushan I de Silva

Exposure to two antigenically distinct SARS-CoV-2 variants broadens neutralization patterns

Vaccine. 2025 Aug 30;62:127459. doi: 10.1016/j.vaccine.2025.127459. Epub 2025 Jul 4.

PMID: 

40617091

Melanie M Schmitt, Annika Rössler, Antonia Netzl, Ludwig Knabl, Albert Falch, Patrick Neckermann, Marta Bermejo-Jambrina, Wegene Borena, Gagandeep Singh, Florian Krammer, Dorothee von Laer, Ralf Wagner, Derek J Smith, Janine Kimpel

Accomplishments and challenges in developing improved influenza vaccines: An evaluation of three years of progress toward the milestones of the influenza vaccines research and development roadmap

Vaccine. 2025 Aug 13;61:127431. doi: 10.1016/j.vaccine.2025.127431. Epub 2025 Jul 1.

PMID: 

40602349

Julia T Ostrowsky, Natalie C Vestin, Angela J Mehr, Angela K Ulrich, Lauren Bigalke, Joseph S Bresee, Martin H Friede, Bruce G Gellin, Keith P Klugman, Usman N Nakakana, Tian Yun Wang, Charlotte L Weller, Michael T Osterholm, Eve M Lackritz, Kristine A Moore, Influenza Vaccines R and D Roadmap Taskforce

Phase 2/3 study evaluating safety, immunogenicity, and noninferiority of single booster dose of AVX/COVID-12 vaccine

Sci Adv. 2025 Jun 27;11(26):eadq2887. doi: 10.1126/sciadv.adq2887. Epub 2025 Jun 27.

PMID: 

40577471

Constantino López-Macías, Martha Torres, Brenda Armenta-Copca, Niels H Wacher, Arturo Galindo-Fraga, Laura Castro-Castrezana, Andrea Alicia Colli-Domínguez, Edgar Cervantes-Trujano, Isabel Erika Rucker-Joerg, Fernando Lozano-Patiño, Juan José Rivera-Alcocer, Abraham Simón-Campos, Efrén Alberto Sánchez-Campos, Rafael Aguirre-Rivero, Alejandro José Muñiz-Carvajal, Luis Del Carpio-Orantes, Francisco Márquez-Díaz, Tania Rivera-Hernández, Alejandro Torres-Flores, Luis Ramírez-Martínez, Georgina Paz-De la Rosa, Oscar Rojas-Martínez, Alejandro Suárez-Martínez, Gustavo Peralta-Sánchez, Claudia Carranza, Esmeralda Juárez, Horacio Zamudio-Meza, Laura E Carreto-Binaghi, Mercedes Viettri, Damaris Romero-Rodríguez

Mendelian Randomisation: Concepts, Opportunities, Challenges, and Future Directions

Glob Heart. 2025 Jun 17;20(1):54. doi: 10.5334/gh.1438. eCollection 2025.

PMID: 

40547872

Sophie C de Ruiter, Lena Tschiderer, Diederick E Grobbee, Peter Willeit, Hester M den Ruijter, A Floriaan Schmidt, Sanne A E Peters

Combination of recombinant neuraminidase with cHA-based inactivated split vaccines improves the breadth of cross-reactivity and protection against influenza viruses in mice

Vaccine. 2025 Aug 13;61:127388. doi: 10.1016/j.vaccine.2025.127388. Epub 2025 Jun 12.

PMID: 

40513214

Eduard Puente-Massaguer, Kirill Vasilev, Florian Krammer

Differentially expressed ncRNAs as key regulators in infection of human bronchial epithelial cells by the SARS-CoV-2 Delta variant

Mol Ther Nucleic Acids. 2025 May 14;36(2):102559. doi: 10.1016/j.omtn.2025.102559. eCollection 2025 Jun 10.

PMID: 

40510596

Glory Ranches, Hubert Hackl, Viktoria Zaderer, Melanie Ploner, Wilfried Posch, Doris Wilflingseder, Kai Kummer, Alexander Hüttenhofer

A review of currently licensed mucosal COVID-19 vaccines

Vaccine. 2025 Aug 13;61:127356. doi: 10.1016/j.vaccine.2025.127356. Epub 2025 Jun 6.

PMID: 

40482457

Alina Tscherne, Florian Krammer
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