Publications

Conventional and non-conventional antigen-binding sites promote the development and function of chronic lymphocytic leukemia stereotyped subset #4 clones

Front Immunol. 2025 Aug 21;16:1607189. doi: 10.3389/fimmu.2025.1607189. eCollection 2025.

PMID: 

40918146

Yun Liu, Dzmitry Padhorny, Rosa Catera, Antonella Nicolo, Xiao-Jie Yan, Stan Xiaogang Li, Anastasia Iatrou, Andrea N Mazzarello, Noemi Destefani, Steven L Allen, Jonathan E Kolitz, Kanti R Rai, Massimo Degano, Paolo P Ghia, Charles C Chu, Florian Krammer, Hassan Jumaa, Kostas Stamatopoulos, Dima Kozakov, Nicholas Chiorazzi

Innate and T-cellular immune responses to sequential vaccination with chimeric hemagglutinin split influenza virus vaccines in mice

Vaccine. 2025 Sep 17;63:127626. doi: 10.1016/j.vaccine.2025.127626. Epub 2025 Aug 27.

PMID: 

40876140

Kirill Vasilev, Eduard Puente-Massaguer, Irene Hoxie, Kaitlyn Bushfield, Florian Krammer

Human monoclonal antibodies targeting A35 protect from death caused by mpox

Cell. 2025 Oct 30;188(22):6236-6252.e18. doi: 10.1016/j.cell.2025.08.004. Epub 2025 Aug 26.

PMID: 

40865529

Raianna F Fantin, Meng Yuan, Seok-Chan Park, Bailey Bozarth, Hallie Cohn, Maxinne Ignacio, Patricia Earl, Alesandro Civljak, Gabriel Laghlali, Ding Zhang, Xueyong Zhu, Jameson Crandell, Valter Monteiro, Jordan J Clark, Catherine Cotter, Martin Burkhardt, Gagandeep Singh, Prajakta Warang, Juan García-Bernalt Diego, Komal Srivastava, Luz A Lugo, Lauren Pischel, PVI study group, Inci Yildirim, Saad B Omer, Daniel da Silva, Florian Krammer, Goran Bajic, Viviana Simon, Michael Schotsaert

Mucosal COVID-19 vaccines in clinical development

Vaccine. 2025 Sep 17;63:127602. doi: 10.1016/j.vaccine.2025.127602. Epub 2025 Aug 22.

PMID: 

40848675

Alina Tscherne, Weina Sun, Sean T H Liu, Florian Krammer

Characterization of the glycoproteins of fish and amphibian influenza B-like viruses

Sci Adv. 2025 Aug 22;11(34):eady8610. doi: 10.1126/sciadv.ady8610. Epub 2025 Aug 22.

PMID: 

40845102

Gagandeep Singh, Jiachen Huang, Disha Bhavsar, Kirill Vasilev, James A Ferguson, Geert-Jan Boons, Viviana Simon, Robert P de Vries, Julianna Han, Andrew Ward, Florian Krammer

A clade 2.3.4.4b H5N1 virus vaccine that elicits cross-protective antibodies against conserved domains of H5 and N1 glycoproteins

bioRxiv [Preprint]. 2025 Aug 14:2025.08.14.670375. doi: 10.1101/2025.08.14.670375.

PMID: 

40832286

Eduard Puente-Massaguer, Thales Galdino Andrade, Michael J Scherm, Kirill Vasilev, Hassanein Abozeid, Alesandra J Rodriguez, Josh Yueh, Disha Bhavsar, John D Campbell, Dong Yu, Richard J Webby, Yoshihiro Kawaoka, Gabriele Neumann, Julianna Han, Andrew B Ward, Florian Krammer

Functional and epitope specific monoclonal antibody discovery directly from immune sera using cryo-EM

Sci Adv. 2025 Aug 15;11(33):eadv8257. doi: 10.1126/sciadv.adv8257. Epub 2025 Aug 15.

PMID: 

40815640

James A Ferguson, Sai Sundar Rajan Raghavan, Garazi Peña Alzua, Disha Bhavsar, Jiachen Huang, Alesandra J Rodriguez, Jonathan L Torres, Maria Bottermann, Julianna Han, Florian Krammer, Facundo D Batista, Andrew B Ward

From first infection to reinfection: Comparing Nucleocapsid antibody kinetics in vaccinated and unvaccinated adults

Vaccine. 2025 Aug 30;62:127593. doi: 10.1016/j.vaccine.2025.127593. Epub 2025 Aug 13.

PMID: 

40812020

Kathleen M Lindsey, Zachary Farrell, Rebecca Tutino, Theresa Kowalski-Dobson, Zijin Chu, Carmen Gherasim, Shuwei Cai, Gabriel Simjanovski, David Manthei, Emily Stoneman, Florian Krammer, Riccardo Valdez, Aubree Gordon

Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitope

Cell Rep. 2025 Aug 26;44(8):116122. doi: 10.1016/j.celrep.2025.116122. Epub 2025 Aug 12.

PMID: 

40803328

Vishal N Rao, Iden A Sapse, Hallie Cohn, Duck-Kyun Yoo, Pei Tong, Jordan J Clark, Bailey Bozarth, Yuexing Chen, Komal Srivastava, Gagandeep Singh, Florian Krammer, Viviana Simon, Duane R Wesemann, Goran Bajic, Camila H Coelho

Molecular organization of the New World arenavirus spike glycoprotein complex

Nat Microbiol. 2025 Sep;10(9):2207-2220. doi: 10.1038/s41564-025-02085-6. Epub 2025 Aug 8.

PMID: 

40781447

Colin J Mann, Pan Yang, Daniel Olal, Xiaoyi Fan, Katherine Nabel Smith, Lars E Clark, Florian Krammer, Yuemin Bian, Jonathan Abraham
...6...