Publications

Eosinophil innate immune memory after bacterial skin infection promotes allergic lung inflammation

Sci Immunol. 2025 Apr 4;10(106):eadp6231. doi: 10.1126/sciimmunol.adp6231. Epub 2025 Apr 4.

PMID: 

40184438

Mariem Radhouani, Asma Farhat, Anna Hakobyan, Sophie Zahalka, Lisabeth Pimenov, Alina Fokina, Anastasiya Hladik, Karin Lakovits, Jessica Brösamlen, Vojtech Dvorak, Natalia Nunes, Andreas Zech, Marco Idzko, Thomas Krausgruber, Jörg Köhl, Ozge Uluckan, Jiri Kovarik, Kai Hoehlig, Axel Vater, Margret Eckhard, Andy Sombke, Nikolaus Fortelny, Jörg Menche, Sylvia Knapp, Philipp Starkl

Identification of a seasonal influenza vaccine-induced broadly protective neuraminidase antibody

J Exp Med. 2025 Jun 2;222(6):e20241930. doi: 10.1084/jem.20241930. Epub 2025 Apr 3.

PMID: 

40178595

Anders Madsen, Nisreen M A Okba, Tossapol Pholcharee, Hanover C Matz, Huibin Lv, Maria Ibanez Trullen, Julian Q Zhou, Jackson S Turner, Aaron J Schmitz, Fangjie Han, Stephen C Horvath, Sameer Kumar Malladi, Florian Krammer, Nicholas C Wu, Ali H Ellebedy

Mucosal multivalent NDV-based vaccine provides cross-reactive immune responses against SARS-CoV-2 variants in animal models

Front Immunol. 2025 Mar 17;16:1524477. doi: 10.3389/fimmu.2025.1524477. eCollection 2025.

PMID: 

40165947

Irene González-Domínguez, Adam Abdeljawad, Tsoi Ying Lai, Marta Boza, Stephen McCroskery, Nicholas Lemus, Stefan Slamanig, Gagandeep Singh, Prajakta Warang, Temima Yellin, Anass Abbad, Juan Manuel Carreño, Victoria Dolange, Jose Luis Martínez-Guevara, Gagandeep Singh, Marina Barcena-Varela, Lauren A Chang, Michael Schotsaert, Florian Krammer, Peter Palese, Weina Sun

Convergent and clonotype-enriched mutations in the light chain drive affinity maturation of a public antibody

bioRxiv [Preprint]. 2025 Mar 10:2025.03.07.642041. doi: 10.1101/2025.03.07.642041.

PMID: 

40161664

Vishal Rao, Iden Sapse, Hallie Cohn, Duck-Kyun Yoo, Pei Tong, Jordan Clark, Bailey Bozarth, Yuexing Chen, Komal Srivastava, Gagandeep Singh, Florian Krammer, Viviana Simon, Duane Wesemann, Goran Bajic, Camila H Coelho

An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence

Sci Immunol. 2025 Mar 28;10(105):eadk5041. doi: 10.1126/sciimmunol.adk5041. Epub 2025 Mar 28.

PMID: 

40153488

Asma Farhat, Mariem Radhouani, Florian Deckert, Sophie Zahalka, Lisabeth Pimenov, Alina Fokina, Anna Hakobyan, Felicitas Oberndorfer, Jessica Brösamlen, Anastasiya Hladik, Karin Lakovits, Fanzhe Meng, Federica Quattrone, Louis Boon, Cornelia Vesely, Philipp Starkl, Nicole Boucheron, Jörg Menche, Joris van der Veeken, Wilfried Ellmeier, Anna-Dorothea Gorki, Clarissa Campbell, Riem Gawish, Sylvia Knapp

Highly pathogenic avian influenza H5N1: history, current situation, and outlook

J Virol. 2025 Apr 15;99(4):e0220924. doi: 10.1128/jvi.02209-24. Epub 2025 Mar 27.

PMID: 

40145745

Florian Krammer, Enikö Hermann, Angela L Rasmussen

Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity

Cell Rep Med. 2025 Apr 15;6(4):102035. doi: 10.1016/j.xcrm.2025.102035. Epub 2025 Mar 21.

PMID: 

40120578

Nicholas J Tursi, Sachchidanand Tiwari, Nicole Bedanova, Toshitha Kannan, Elizabeth Parzych, Nisreen Okba, Kevin Liaw, András Sárközy, Cory Livingston, Maria Ibanez Trullen, Ebony N Gary, Máté Vadovics, Niklas Laenger, Jennifer Londregan, Mohammad Suhail Khan, Serena Omo-Lamai, Hiromi Muramatsu, Kerry Blatney, Casey Hojecki, Viviane Machado, Igor Maricic, Trevor R F Smith, Laurent M Humeau, Ami Patel, Andrew Kossenkov, Jacob S Brenner, David Allman, Florian Krammer, Norbert Pardi, David B Weiner

The diagnosis of mucormycosis by PCR in patients at risk: a systematic review and meta-analysis

EClinicalMedicine. 2025 Feb 22;81:103115. doi: 10.1016/j.eclinm.2025.103115. eCollection 2025 Mar.

PMID: 

40083443

Lottie Brown, Lena Tschiderer, Alexandre Alanio, Rosemary A Barnes, Sharon C-A Chen, Massimo Cogliati, Mario Cruciani, J Peter Donnelly, Ferry Hagen, Catriona Halliday, Lena Klingspor, Katrien Lagrou, Willem Melchers, Laurence Millon, Florent Morio, Elena Salvador, Giacomo Stroffolini, Markus Ruhnke, Stephanie Toepfer, Karin van Dijk, Andrew M Borman, María José Buitrago, Rebecca Gorton, Jürgen Löffller, Riina Rautemaa-Richardson, Boualem Sendid, Peter Willeit, P Lewis White, Michaela Lackner

Next-generation seasonal influenza virus vaccines need a neuraminidase component

Vaccine. 2025 Apr 30;54:126994. doi: 10.1016/j.vaccine.2025.126994. Epub 2025 Mar 9.

PMID: 

40058285

Florian Krammer

XBB.1.5 monovalent vaccine induces lasting cross-reactive responses to SARS-CoV-2 variants such as HV.1 and JN.1, as well as SARS-CoV-1, but elicits limited XBB.1.5 specific antibodies

mBio. 2025 Apr 9;16(4):e0360724. doi: 10.1128/mbio.03607-24. Epub 2025 Mar 5.

PMID: 

40042313

Juan Manuel Carreño, Brian Lerman, Gagandeep Singh, Anass Abbad, Temima Yellin, Jordan Ehrenhaus, Miriam Fried, Jessica R Nardulli, Hyun Min Kang, Lubbertus C F Mulder, Charles Gleason, Komal Srivastava, PVI study group, Viviana Simon, Florian Krammer
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