Convergent and clonotype-enriched mutations in the light chain drive affinity maturation of a public antibody
bioRxiv [Preprint]. 2025 Mar 10:2025.03.07.642041. doi: 10.1101/2025.03.07.642041.
PMID:
Vishal Rao, Iden Sapse, Hallie Cohn, Duck-Kyun Yoo, Pei Tong, Jordan Clark, Bailey Bozarth, Yuexing Chen, Komal Srivastava, Gagandeep Singh, Florian Krammer, Viviana Simon, Duane Wesemann, Goran Bajic, Camila H Coelho
An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence
Sci Immunol. 2025 Mar 28;10(105):eadk5041. doi: 10.1126/sciimmunol.adk5041. Epub 2025 Mar 28.
PMID:
Asma Farhat, Mariem Radhouani, Florian Deckert, Sophie Zahalka, Lisabeth Pimenov, Alina Fokina, Anna Hakobyan, Felicitas Oberndorfer, Jessica Brösamlen, Anastasiya Hladik, Karin Lakovits, Fanzhe Meng, Federica Quattrone, Louis Boon, Cornelia Vesely, Philipp Starkl, Nicole Boucheron, Jörg Menche, Joris van der Veeken, Wilfried Ellmeier, Anna-Dorothea Gorki, Clarissa Campbell, Riem Gawish, Sylvia Knapp
Highly pathogenic avian influenza H5N1: history, current situation, and outlook
J Virol. 2025 Apr 15;99(4):e0220924. doi: 10.1128/jvi.02209-24. Epub 2025 Mar 27.
PMID:
Florian Krammer, Enikö Hermann, Angela L Rasmussen
Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity
Cell Rep Med. 2025 Apr 15;6(4):102035. doi: 10.1016/j.xcrm.2025.102035. Epub 2025 Mar 21.
PMID:
Nicholas J Tursi, Sachchidanand Tiwari, Nicole Bedanova, Toshitha Kannan, Elizabeth Parzych, Nisreen Okba, Kevin Liaw, András Sárközy, Cory Livingston, Maria Ibanez Trullen, Ebony N Gary, Máté Vadovics, Niklas Laenger, Jennifer Londregan, Mohammad Suhail Khan, Serena Omo-Lamai, Hiromi Muramatsu, Kerry Blatney, Casey Hojecki, Viviane Machado, Igor Maricic, Trevor R F Smith, Laurent M Humeau, Ami Patel, Andrew Kossenkov, Jacob S Brenner, David Allman, Florian Krammer, Norbert Pardi, David B Weiner
The diagnosis of mucormycosis by PCR in patients at risk: a systematic review and meta-analysis
EClinicalMedicine. 2025 Feb 22;81:103115. doi: 10.1016/j.eclinm.2025.103115. eCollection 2025 Mar.
PMID:
Lottie Brown, Lena Tschiderer, Alexandre Alanio, Rosemary A Barnes, Sharon C-A Chen, Massimo Cogliati, Mario Cruciani, J Peter Donnelly, Ferry Hagen, Catriona Halliday, Lena Klingspor, Katrien Lagrou, Willem Melchers, Laurence Millon, Florent Morio, Elena Salvador, Giacomo Stroffolini, Markus Ruhnke, Stephanie Toepfer, Karin van Dijk, Andrew M Borman, MarÃa José Buitrago, Rebecca Gorton, Jürgen Löffller, Riina Rautemaa-Richardson, Boualem Sendid, Peter Willeit, P Lewis White, Michaela Lackner
Next-generation seasonal influenza virus vaccines need a neuraminidase component
Vaccine. 2025 Apr 30;54:126994. doi: 10.1016/j.vaccine.2025.126994. Epub 2025 Mar 9.
PMID:
Florian Krammer
XBB.1.5 monovalent vaccine induces lasting cross-reactive responses to SARS-CoV-2 variants such as HV.1 and JN.1, as well as SARS-CoV-1, but elicits limited XBB.1.5 specific antibodies
mBio. 2025 Apr 9;16(4):e0360724. doi: 10.1128/mbio.03607-24. Epub 2025 Mar 5.
PMID:
Juan Manuel Carreño, Brian Lerman, Gagandeep Singh, Anass Abbad, Temima Yellin, Jordan Ehrenhaus, Miriam Fried, Jessica R Nardulli, Hyun Min Kang, Lubbertus C F Mulder, Charles Gleason, Komal Srivastava, PVI study group, Viviana Simon, Florian Krammer
Safety and immunogenicity of an inactivated recombinant Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Results of a randomized vaccine-controlled phase I ADAPTCOV trial in Brazil
Vaccine. 2025 Apr 11;52:126680. doi: 10.1016/j.vaccine.2024.126680. Epub 2025 Mar 3.
PMID:
Érique José Farias Peixoto de Miranda, Rodrigo T Calado, Fernanda Castro Boulos, José Alfredo de Sousa Moreira, Fabiane Fernandes Machado, Maria Aparecida Alves Leite Dos Santos Almeida, Marcia Cristina Oliveira Da Rocha, Vanessa Infante, Laina D Mercer, Richard Hjorth, Rami Scharf, Jessica White, Christina Polyak, Rama Raghunandan, Adolfo GarcÃa-Sastre, Weina Sun, Peter Palese, Florian Krammer, Bruce Innis, Cristiano Gonçalves Pereira, Esper Georges Kallas
Clade 2.3.4.4b H5N1 neuraminidase has a long stalk, which is in contrast to most highly pathogenic H5N1 viruses circulating between 2002 and 2020
mBio. 2025 Apr 9;16(4):e0398924. doi: 10.1128/mbio.03989-24. Epub 2025 Feb 26.
PMID:
Enikő Hermann, Florian Krammer
Factors Associated with Mortality in Nosocomial Lower Respiratory Tract Infections: An ENIRRI Analysis
Antibiotics (Basel). 2025 Jan 26;14(2):127. doi: 10.3390/antibiotics14020127.
PMID:
Luis Felipe Reyes, Antoni Torres, Juan Olivella-Gomez, Elsa D Ibáñez-Prada, Saad Nseir, Otavio T Ranzani, Pedro Povoa, Emilio Diaz, Marcus J Schultz, Alejandro H RodrÃguez, Cristian C Serrano-Mayorga, Gennaro De Pascale, Paolo Navalesi, Szymon Skoczynski, Mariano Esperatti, Luis Miguel Coelho, Andrea Cortegiani, Stefano Aliberti, Anselmo Caricato, Helmut J F Salzer, Adrian Ceccato, Rok Civljak, Paolo Maurizio Soave, Charles-Edouard Luyt, Pervin Korkmaz Ekren, Fernando Rios, Joan Ramon Masclans, Judith Marin, Silvia Iglesias-Moles, Stefano Nava