Publications

Serum matters: human platelet lysate enables physiological modeling of HIV-1 infection in dendritic cells

Front Immunol. 2025 Sep 17;16:1661425. doi: 10.3389/fimmu.2025.1661425. eCollection 2025.

PMID: 

Paul Schweighofer, Magdalena Erlacher, Wilfried Posch, Doris Wilflingseder

Chimeric hemagglutinin-based universal influenza mRNA vaccine induces protective immunity and bone marrow plasma cells in rhesus macaques

Cell Rep Med. 2025 Oct 21;6(10):102369. doi: 10.1016/j.xcrm.2025.102369. Epub 2025 Sep 25.

PMID: 

Tiffany M Styles, Akil Akhtar, Chunyang Gu, Gabriele Neumann, Hiromi Muramatsu, Justine S McPartlan, Poulami Talukder, Derrik Gratz, Kasey Stokdyk, Hannah L Turner, James A Ferguson, Alesandra J Rodriguez, Madhumathi Loganathan, Benjamin Francis, Anass Abbad, Ghania Chikh, Ying K Tam, Zhaohui S Qin, Julianna Han, Juan Manuel Carreño, Andrew B Ward, Jasdave S Chahal, Christian W Mandl, Norbert Pardi, Yoshihiro Kawaoka, Florian Krammer, Rafi Ahmed, Rama R Amara

Assessment of critical bioprocess parameters for broadly cross-reactive chimeric hemagglutinin influenza virus vaccines

Vaccine. 2025 Oct 3;64:127671. doi: 10.1016/j.vaccine.2025.127671. Epub 2025 Sep 18.

PMID: 

Michael J Scherm, Robert Hölzl, Irene González-Domínguez, Richard Hjorth, Sean S Chiou, Maureen F Maughan, Diana Martik, Florian Krammer, Eduard Puente-Massaguer

Empirical antifungal treatment of critically ill patients with influenza-associated acute respiratory distress syndrome: A propensity score weighted observational study

Clin Infect Dis. 2025 Sep 15:ciaf507. doi: 10.1093/cid/ciaf507. Online ahead of print.

PMID: 

Stefan Hatzl, Lisa Kriegl, Christina Geiger, Caroline Wilhelmer, Alexander C Reisinger, Markus Keldorfer, Julia Auinger, Gernot Schilcher, Florian Krammer, Philipp Eller, Robert Krause

Conventional and non-conventional antigen-binding sites promote the development and function of chronic lymphocytic leukemia stereotyped subset #4 clones

Front Immunol. 2025 Aug 21;16:1607189. doi: 10.3389/fimmu.2025.1607189. eCollection 2025.

PMID: 

Yun Liu, Dzmitry Padhorny, Rosa Catera, Antonella Nicolo, Xiao-Jie Yan, Stan Xiaogang Li, Anastasia Iatrou, Andrea N Mazzarello, Noemi Destefani, Steven L Allen, Jonathan E Kolitz, Kanti R Rai, Massimo Degano, Paolo P Ghia, Charles C Chu, Florian Krammer, Hassan Jumaa, Kostas Stamatopoulos, Dima Kozakov, Nicholas Chiorazzi

Innate and T-cellular immune responses to sequential vaccination with chimeric hemagglutinin split influenza virus vaccines in mice

Vaccine. 2025 Sep 17;63:127626. doi: 10.1016/j.vaccine.2025.127626. Epub 2025 Aug 27.

PMID: 

Kirill Vasilev, Eduard Puente-Massaguer, Irene Hoxie, Kaitlyn Bushfield, Florian Krammer

Human monoclonal antibodies targeting A35 protect from death caused by mpox

Cell. 2025 Oct 30;188(22):6236-6252.e18. doi: 10.1016/j.cell.2025.08.004. Epub 2025 Aug 26.

PMID: 

Raianna F Fantin, Meng Yuan, Seok-Chan Park, Bailey Bozarth, Hallie Cohn, Maxinne Ignacio, Patricia Earl, Alesandro Civljak, Gabriel Laghlali, Ding Zhang, Xueyong Zhu, Jameson Crandell, Valter Monteiro, Jordan J Clark, Catherine Cotter, Martin Burkhardt, Gagandeep Singh, Prajakta Warang, Juan García-Bernalt Diego, Komal Srivastava, Luz A Lugo, Lauren Pischel, PVI study group, Inci Yildirim, Saad B Omer, Daniel da Silva, Florian Krammer, Goran Bajic, Viviana Simon, Michael Schotsaert

Mucosal COVID-19 vaccines in clinical development

Vaccine. 2025 Sep 17;63:127602. doi: 10.1016/j.vaccine.2025.127602. Epub 2025 Aug 22.

PMID: 

Alina Tscherne, Weina Sun, Sean T H Liu, Florian Krammer

Characterization of the glycoproteins of fish and amphibian influenza B-like viruses

Sci Adv. 2025 Aug 22;11(34):eady8610. doi: 10.1126/sciadv.ady8610. Epub 2025 Aug 22.

PMID: 

Gagandeep Singh, Jiachen Huang, Disha Bhavsar, Kirill Vasilev, James A Ferguson, Geert-Jan Boons, Viviana Simon, Robert P de Vries, Julianna Han, Andrew Ward, Florian Krammer

A clade 2.3.4.4b H5N1 virus vaccine that elicits cross-protective antibodies against conserved domains of H5 and N1 glycoproteins

bioRxiv [Preprint]. 2025 Aug 14:2025.08.14.670375. doi: 10.1101/2025.08.14.670375.

PMID: 

Eduard Puente-Massaguer, Thales Galdino Andrade, Michael J Scherm, Kirill Vasilev, Hassanein Abozeid, Alesandra J Rodriguez, Josh Yueh, Disha Bhavsar, John D Campbell, Dong Yu, Richard J Webby, Yoshihiro Kawaoka, Gabriele Neumann, Julianna Han, Andrew B Ward, Florian Krammer