Highly pathogenic avian influenza H5N1: history, current situation, and outlook
J Virol. 2025 Apr 15;99(4):e0220924. doi: 10.1128/jvi.02209-24. Epub 2025 Mar 27.
PMID:
Florian Krammer, Enikö Hermann, Angela L Rasmussen
Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity
Cell Rep Med. 2025 Apr 15;6(4):102035. doi: 10.1016/j.xcrm.2025.102035. Epub 2025 Mar 21.
PMID:
Nicholas J Tursi, Sachchidanand Tiwari, Nicole Bedanova, Toshitha Kannan, Elizabeth Parzych, Nisreen Okba, Kevin Liaw, András Sárközy, Cory Livingston, Maria Ibanez Trullen, Ebony N Gary, Máté Vadovics, Niklas Laenger, Jennifer Londregan, Mohammad Suhail Khan, Serena Omo-Lamai, Hiromi Muramatsu, Kerry Blatney, Casey Hojecki, Viviane Machado, Igor Maricic, Trevor R F Smith, Laurent M Humeau, Ami Patel, Andrew Kossenkov, Jacob S Brenner, David Allman, Florian Krammer, Norbert Pardi, David B Weiner
The diagnosis of mucormycosis by PCR in patients at risk: a systematic review and meta-analysis
EClinicalMedicine. 2025 Feb 22;81:103115. doi: 10.1016/j.eclinm.2025.103115. eCollection 2025 Mar.
PMID:
Lottie Brown, Lena Tschiderer, Alexandre Alanio, Rosemary A Barnes, Sharon C-A Chen, Massimo Cogliati, Mario Cruciani, J Peter Donnelly, Ferry Hagen, Catriona Halliday, Lena Klingspor, Katrien Lagrou, Willem Melchers, Laurence Millon, Florent Morio, Elena Salvador, Giacomo Stroffolini, Markus Ruhnke, Stephanie Toepfer, Karin van Dijk, Andrew M Borman, María José Buitrago, Rebecca Gorton, Jürgen Löffller, Riina Rautemaa-Richardson, Boualem Sendid, Peter Willeit, P Lewis White, Michaela Lackner
Next-generation seasonal influenza virus vaccines need a neuraminidase component
Vaccine. 2025 Apr 30;54:126994. doi: 10.1016/j.vaccine.2025.126994. Epub 2025 Mar 9.
PMID:
Florian Krammer
XBB.1.5 monovalent vaccine induces lasting cross-reactive responses to SARS-CoV-2 variants such as HV.1 and JN.1, as well as SARS-CoV-1, but elicits limited XBB.1.5 specific antibodies
mBio. 2025 Apr 9;16(4):e0360724. doi: 10.1128/mbio.03607-24. Epub 2025 Mar 5.
PMID:
Juan Manuel Carreño, Brian Lerman, Gagandeep Singh, Anass Abbad, Temima Yellin, Jordan Ehrenhaus, Miriam Fried, Jessica R Nardulli, Hyun Min Kang, Lubbertus C F Mulder, Charles Gleason, Komal Srivastava, PVI study group, Viviana Simon, Florian Krammer
Safety and immunogenicity of an inactivated recombinant Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Results of a randomized vaccine-controlled phase I ADAPTCOV trial in Brazil
Vaccine. 2025 Apr 11;52:126680. doi: 10.1016/j.vaccine.2024.126680. Epub 2025 Mar 3.
PMID:
Érique José Farias Peixoto de Miranda, Rodrigo T Calado, Fernanda Castro Boulos, José Alfredo de Sousa Moreira, Fabiane Fernandes Machado, Maria Aparecida Alves Leite Dos Santos Almeida, Marcia Cristina Oliveira Da Rocha, Vanessa Infante, Laina D Mercer, Richard Hjorth, Rami Scharf, Jessica White, Christina Polyak, Rama Raghunandan, Adolfo García-Sastre, Weina Sun, Peter Palese, Florian Krammer, Bruce Innis, Cristiano Gonçalves Pereira, Esper Georges Kallas
Clade 2.3.4.4b H5N1 neuraminidase has a long stalk, which is in contrast to most highly pathogenic H5N1 viruses circulating between 2002 and 2020
mBio. 2025 Apr 9;16(4):e0398924. doi: 10.1128/mbio.03989-24. Epub 2025 Feb 26.
PMID:
Enikő Hermann, Florian Krammer
Factors Associated with Mortality in Nosocomial Lower Respiratory Tract Infections: An ENIRRI Analysis
Antibiotics (Basel). 2025 Jan 26;14(2):127. doi: 10.3390/antibiotics14020127.
PMID:
Luis Felipe Reyes, Antoni Torres, Juan Olivella-Gomez, Elsa D Ibáñez-Prada, Saad Nseir, Otavio T Ranzani, Pedro Povoa, Emilio Diaz, Marcus J Schultz, Alejandro H Rodríguez, Cristian C Serrano-Mayorga, Gennaro De Pascale, Paolo Navalesi, Szymon Skoczynski, Mariano Esperatti, Luis Miguel Coelho, Andrea Cortegiani, Stefano Aliberti, Anselmo Caricato, Helmut J F Salzer, Adrian Ceccato, Rok Civljak, Paolo Maurizio Soave, Charles-Edouard Luyt, Pervin Korkmaz Ekren, Fernando Rios, Joan Ramon Masclans, Judith Marin, Silvia Iglesias-Moles, Stefano Nava
Europe needs a sustainably funded influenza research and response network
Lancet Infect Dis. 2025 Apr;25(4):369-372. doi: 10.1016/S1473-3099(25)00068-4. Epub 2025 Feb 17.
PMID:
Florian Krammer, Wendy S Barclay, Martin Beer, Ian H Brown, Rebecca Jane Cox, Menno D de Jong, Ervin Fodor, Ron A M Fouchier, Gülsah Gabriel, Adolfo García-Sastre, Raquel Guiomar, Peter Horby, Marion Koopmans, Nicola S Lewis, Stefania Maggi, Isabella Monne, Nadia Naffakh, Hanna Nohynek, Albert Osterhaus, Katarina Prosenc, Roman Prymula, Rino Rappuoli, Monika Redlberger-Fritz, Guus F Rimmelzwaan, Colin A Russell, Xavier Saelens, Martin Schwemmle, Derek J Smith, Silke Stertz, Paula A Tähtinen
Estimates of SARS-CoV-2 Infections and Population Immunity After the COVID-19 Pandemic in Austria: Analysis of National Wastewater Data
J Infect Dis. 2025 Jun 2;231(5):e921-e928. doi: 10.1093/infdis/jiaf054.
PMID:
Uwe Riedmann, Alena Chalupka, Lukas Richter, Martin Sprenger, Wolfgang Rauch, Hannes Schenk, Robert Krause, Peter Willeit, Herbert Oberacher, Tracy Beth Høeg, John P A Ioannidis, Stefan Pilz